Nonprofits in Durham, NC
501(c)(3) nonprofit organizations — IRS Exempt Organizations Business Master File (2026-02)
Overview
Source: IRS Exempt Organizations BMFTotal Nonprofits
1,964
Total Assets
$50.7B
Orgs with >$1M Assets
246
Per 10K Residents
68.1
nonprofits
+40.8% vs 250K-500K avg
Nonprofits by Category
Source: IRS / NTEE ClassificationReligion279
Education263
Human Services197
Arts & Culture142
Health Care87
Philanthropy83
Community Improvement82
Recreation & Sports76
Youth Development74
International44
Environment38
Crime & Legal32
Mental Health27
Food & Agriculture25
Public Benefit24
Housing & Shelter21
Civil Rights21
Animal-Related20
Employment20
Science & Tech19
Voluntary Health17
Medical Research17
Social Science10
Public Safety6
Unknown5
Mutual Benefit3
Nonprofits per 10K Residents vs Similar Cities
Source: IRS BMF + Census ACSCompared to cities with population 250,000 - 500,000
Largest Nonprofits in Durham
Source: IRS Exempt Organizations BMF| Organization | Category | Assets | Income | Est. |
|---|---|---|---|---|
| DUKE UNIVERSITY | Education | $21.2B | $4.5B | 1939 |
| DUKE UNIVERSITY HEALTH SYSTEM INC | Health Care | $8.6B | $7.2B | 1998 |
| GOTHIC CORPORATION | Education | $8.2B | $1.8B | 1993 |
| SELF HELP VENTURES FUND | Community Improvement | $3.4B | $191.2M | 1984 |
| GOTHIC HSP CORPORATION | Health Care | $2.5B | $490.2M | 2010 |
| RESEARCH TRIANGLE INSTITUTE | Science & Tech | $935.9M | $1.5B | 1960 |
| THE UNITED METHODIST RETIREMENT HOMES INC | Philanthropy | $476.3M | $102.2M | 2011 |
| FAMILY HEALTH INTERNATIONAL | International | $348.3M | $800.1M | 1974 |
| TRIANGLE COMMUNITY FOUNDATION | Philanthropy | $311.2M | $138.6M | 1984 |
| DUKE HEALTH INTEGRATED PRACTICE INC | — | $249.1M | $1.3B | 2021 |
| NEW DURHAM CORPORATION | Community Improvement | $242.3M | $11.1M | 1987 |
| L C IND INC | Human Services | $237.3M | $393.8M | 1960 |
| BLUE CROSS AND BLUE SHIELD OF NORTH CAROLINA FOUNDATION | Philanthropy | $223.3M | $78.4M | 2002 |
| THE FAMILY HEALTH INTERNATIONAL FOUNDATION | International | $200.9M | $36.9M | 1991 |
| TRIANGLE LAND CONSERVANCY INC | Environment | $194.1M | $38.2M | 1983 |
| FOREST AT DUKE INC | Human Services | $183.3M | $37.9M | 1989 |
| DURHAM ACADEMY INC | Education | $118.3M | $59.1M | 1961 |
| GOODWILL INDUSTRIES OF EASTERN NORTH CAROLINA INC | Employment | $117.9M | $52.1M | 1964 |
| THE RAUCH FAMILY FOUNDATION | — | $107.7M | $19.0M | 1990 |
| SELF-HELP COMMUNITY DEVELOPMENT CORP | Community Improvement | $106.1M | $6.0M | 1996 |
| DUKE UNIVERSITY AFFILIATED PHYSICANS INC | Health Care | $83.1M | $230.5M | 1996 |
| L C INDUSTRIES FOUNDATION | Human Services | $73.1M | $3.6M | 2013 |
| NORTH CAROLINA GLAXOSMITHKLINE FOUNDATION | — | $71.7M | $17.3M | 1986 |
| JUST TRUST FOR EDUCATION | Crime & Legal | $66.9M | $41.4M | 2023 |
| LATINO COMMUNITY DEVELOPMENT CENTER | Human Services | $62.0M | $65.3M | 2002 |
| CENTER FOR COMMUNITY SELF-HELP | Employment | $57.3M | $7.6M | 1981 |
| TRIANGLE RESIDENTIAL OPTIONS FOR SUBSTANCE ABUSERS INC | — | $54.6M | $22.6M | 1994 |
| LAUGHING GULL FOUNDATION | Philanthropy | $53.4M | $7.4M | 2013 |
| NORTH CAROLINA CENTRAL UNIVERSITY FOUNDATION INC | Education | $53.1M | $23.5M | 1974 |
| NC IDEA | Science & Tech | $51.5M | $2.3M | 2002 |
| INTERNATIONAL SOCIETY OF AUTOMATION | Science & Tech | $50.5M | $28.3M | 1982 |
| DIVERS ALERT NETWORK | Recreation & Sports | $49.2M | $13.6M | 1990 |
| CAROLINA FRIENDS SCHOOL | — | $46.7M | $16.1M | 1965 |
| NORTH CAROLINA SCHOOL OF SCIENCE & MATHEMATICS FOUNDATION | — | $45.0M | $7.4M | 1979 |
| VOYAGER FOUNDATION INC | Education | $44.7M | $2.2M | 2013 |
| NORTH CAROLINA BIOTECHNOLOGY CENTER | Science & Tech | $44.0M | $23.3M | 1985 |
| MARY DUKE BIDDLE FOUNDATION | — | $43.0M | $3.8M | 1958 |
| INSTITUTE CAPITAL INC | Community Improvement | $41.3M | $3.3M | 2000 |
| RESCUE LEGACY FUND INC | Religion | $38.9M | $56.1M | 2010 |
| EXCELSIOR CLASSICAL ACADEMY - A CHALLENGE FOUNDATION ACADEMY | Education | $38.0M | $13.3M | 2015 |
| DUKE CORPORATE EDUCATION | Education | $35.5M | $33.1M | 2007 |
| HEALTHY START EDUCATION INC | Education | $35.4M | $11.2M | 1999 |
| ASSOCIATED HEALTH SERVICES INC | Health Care | $33.7M | $69.0M | 1997 |
| HILL CENTER INC | Education | $32.4M | $13.3M | 1998 |
| DURHAM EXCHANGE CLUB INDUSTRIES INC | Employment | $31.9M | $16.4M | 1967 |
| DUKE SCHOOL | — | $30.8M | $16.2M | 1984 |
| THE CATHERINE JEFFERSON FOUNDATION | Philanthropy | $30.6M | $14.0M | 2014 |
| TRINITY SCHOOL OF DURHAM AND CHAPEL HILL INC | Education | $27.7M | $23.0M | 1996 |
| REINVESTMENT PARTNERS | Community Improvement | $27.6M | $18.7M | 1998 |
| DUMAC INC | Education | $27.0M | $33.7M | 2011 |
Durham, NC has 1,964 registered 501(c)(3) nonprofit organizations with combined assets of $50.7B. The most common category is Religion-Related, with 279 organizations. 246 nonprofits have assets exceeding $1 million. That works out to 68.1 nonprofits per 10,000 residents. The oldest active nonprofit dates back to 1937.